LymphedemaV1, Main, Exploration, bibRecord, 000380

Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels.

Identifieur interne : 000380 ( Main/Exploration ); précédent : 000379; suivant : 000381

Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels.

Auteurs : Benjamin F. Arnold [États-Unis] ; Mark J. Van Der Laan [États-Unis] ; Alan E. Hubbard [États-Unis] ; Cathy Steel [États-Unis] ; Joseph Kubofcik [États-Unis] ; Katy L. Hamlin [États-Unis] ; Delynn M. Moss [États-Unis] ; Thomas B. Nutman [États-Unis] ; Jeffrey W. Priest [États-Unis] ; Patrick J. Lammie [États-Unis]

Source :

PLoS neglected tropical diseases [ 1935-2735 ] ; 2017.

RBID : pubmed:28542223

Descripteurs français

English descriptors

KwdEn :
- Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Animals, Antibodies (blood), Child, Child, Preschool, Cross-Sectional Studies, Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (immunology), Female, Gastrointestinal Diseases (epidemiology), Gastrointestinal Diseases (immunology), Haiti (epidemiology), Humans, Infant, Infant, Newborn, Malaria (epidemiology), Malaria (immunology), Male, Middle Aged, Neglected Diseases (epidemiology), Neglected Diseases (immunology), Nigeria (epidemiology), Polynesia (epidemiology), Seroepidemiologic Studies, Serologic Tests (methods), United States (epidemiology), Young Adult.
MESH :
- chemical , blood : Antibodies.
- epidemiology : Elephantiasis, Filarial, Gastrointestinal Diseases, Haiti, Malaria, Neglected Diseases, Nigeria, Polynesia, United States.
- immunology : Elephantiasis, Filarial, Gastrointestinal Diseases, Malaria, Neglected Diseases.
- methods : Serologic Tests.
- Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Animals, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Seroepidemiologic Studies, Young Adult.

Abstract

Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance. Most methods to analyze antibody measurements reduce quantitative antibody levels to seropositive and seronegative groups, but this can be difficult for many pathogens and may provide lower resolution information than quantitative levels. Analysis methods have predominantly maintained a single disease focus, yet integrated surveillance platforms would benefit from methodologies that work across diverse pathogens included in multiplex assays.

DOI: 10.1371/journal.pntd.0005616
PubMed: 28542223

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance. Most methods to analyze antibody measurements reduce quantitative antibody levels to seropositive and seronegative groups, but this can be difficult for many pathogens and may provide lower resolution information than quantitative levels. Analysis methods have predominantly maintained a single disease focus, yet integrated surveillance platforms would benefit from methodologies that work across diverse pathogens included in multiplex assays.</div>
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<name sortKey="Van Der Laan, Mark J" sort="Van Der Laan, Mark J" uniqKey="Van Der Laan M" first="Mark J" last="Van Der Laan">Mark J. Van Der Laan</name>
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   |area=    LymphedemaV1
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   |clé=     pubmed:28542223
   |texte=   Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels.
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Serveur d'exploration sur le lymphœdème

Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels.

Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels.

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	Serveur d'exploration sur le lymphœdème
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